Nothing tells a prospective employer that you are not the right person for his or her job more quickly than a resume that does not match the job description or the stated needs of the employer.
Your resume should be written in a way that reflects your education and accomplishments. Resist the desire to overstate your abilities, education, or achievements. If you overstate, you may appear over-qualified for the positions you are seeking.
And that lovely resume that makes you sound like Superman, Tarzan, and Albert Einstein all rolled into